The Leave vote in the EU referendum was largely comprised of an odd mix of the older demographic with the regions where poverty and inequality are most manifest.
The Tories might have some traction with the over-50s, but the demographic trend will ultimately favour Return over Remain Out over the next decade or so. In other words ideological eurosceptics in the right wing of the Conservative party will need to maintain an obviously uneasy connection with the dis-empowered and downtrodden, presumably via nationalistic/xenophobic rhetoric: the classic snobs and mobs scenario.
I cannot see this lasting at all. To counteract the demographic tendency, the government would have to try to persistently foster the social anger that underlies the protest vote and somehow avoid becoming the target of it.